How to use Calcium 500 + VITAMIN D
Calcium is essential for the development and maintenance of strong bones and teeth (also for normal blood clotting, nerve function and enzyme activity).
It is an essential nutrient throughout life for everyone and is especially important in children, adolescents, breastfeeding and postmenopausal women.
A poor calcium intake can be an important contributory factor in the development of osteoporosis (brittle bones).This combination medication is used to prevent or treat low blood calcium levels in people who do not get enough calcium from their diets. It may be used to treat conditions caused by low calcium levels such as bone loss (osteoporosis), weak bones (osteomalacia/rickets), decreased activity of the parathyroid gland (hypoparathyroidism), and a certain muscle disease (latent tetany). It may also be used in certain patients to make sure they are getting enough calcium (including women who are pregnant, nursing, or postmenopausal, people taking certain medications such as phenytoin, phenobarbital, or prednisone).Calcium plays a very important role in the body. It is necessary for normal functioning of nerves, cells, muscle, and bone. If there is not enough calcium in the blood, then the body will take calcium from bones, thereby weakening bones. Vitamin D helps your body absorb calcium and phosphorus. Having the right amounts of vitamin D, calcium, and phosphorus is important for building and keeping strong bones.
Take this medication by mouth with food. If your product contains calcium citrate, then it may be taken with or without food. Follow all directions on the product package, or take as directed by your doctor. For best absorption, if your total daily dose is more than 600 milligrams, then divide your dose and space it throughout the day. If you have any questions, ask your doctor or pharmacist.
If you are using the liquid form of this medication, carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose.
If you are taking the chewable form of this medication, chew thoroughly before swallowing. If you are taking capsules, swallow each capsule whole.
Do not crush or chew extended-release tablets. Doing so can release all of the drug at once, increasing the risk of side effects. Also, do not split the tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing.
Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day.
If your doctor has recommended that you follow a special diet, it is very important to follow the diet to get the most benefit from this medication and to prevent serious side effects. Do not take other supplements/vitamins unless ordered by your doctor.
What are the side effects of Calcium And Vitamin D Combination (Calcium 500+D)?
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have signs of too much calcium in your body, such as:
- nausea, vomiting, constipation;
- increased thirst or urination;
- muscle weakness, bone pain; or
- confusion, lack of energy, or feeling tired.
Common side effects may include:
- an irregular heartbeat;
- weakness, drowsiness, headache;
- dry mouth, or a metallic taste in your mouth; or
- muscle or bone pain.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
If you are unable to achieve an adequate calcium intake
Despite eating a varied diet and regular meals it may be necessary to supplement
your diet with a calcium preparation. Calcium preparations are available in tablet,
syrup, chewable and effervescent forms and some are available on prescription.
Check the ingredients and amount of calcium they supply. Ask your dietitian or
pharmacist for advice if required. You only need to take the calcium preparation on
the days you do not achieve your requirement.
Vitamin D has several important functions. For example, it helps regulate the amount
of calcium and phosphate in the body. These nutrients are needed to keep bones
and teeth healthy. A lack of vitamin D can lead to bone deformities such as rickets in
children and bone pain and tenderness as a result of a condition called osteomalacia
or osteoporosis in adults.
Good sources of vitamin D
We get most of our vitamin D from sunlight on our skin. The vitamin is made by our body
under the skin in reaction to sunlight. However, if you are out in the sun, take care to cover
up or protect your skin with sunscreen before you turn red or get burnt.
Vitamin D is also found in a small number of foods. Good food sources are:
• oily fish – such as salmon, sardines and mackerel
• fortified fat spreads
• fortified breakfast cereals
• powdered milk.
PREGNANCY & BREASTFEEDING
Can I take Calcium And Vitamin D Combination (Calcium 500+D) if I’m pregnant or breastfeeding?
Ask a doctor before using this product if you are pregnant or breast-feeding. Your dose needs may be different during pregnancy or while you are nursing.
What drugs and food should I avoid while taking Calcium And Vitamin D Combination (Calcium 500+D)?
Ask a doctor or pharmacist before taking any multivitamins, mineral supplements, or antacids while you are taking calcium and vitamin D combination.
DOSAGE GUIDELINES & TIPS
How to take Calcium And Vitamin D Combination (Calcium 500+D)?
Use Calcium And Vitamin D Combination (Calcium 500+D) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Check the label of your calcium and vitamin D combination product to see if it should be taken with or without food.
Take the regular tablet with a full glass of water.
The chewable tablet must be chewed before you swallow it.
Do not crush, chew, or break an extended-release tablet. Swallow it whole.
Calcium and vitamin D may be only part of a complete program of treatment that also includes dietary changes. Learn about the foods that contain calcium and vitamin D.
WHAT TO EXPECT
You may experience mild side effects, such as minor gas or constipation, when taking calcium and vitamin D combination. If this occurs, try increasing your fluid intake or switching to a different brand.
ADDITIONAL DOSAGE INFORMATION
The amount of calcium and vitamin D you require will depend on your age, your gender, how much calcium you get from the foods you eat, and other factors.
Typically, calcium is absorbed best when it’s taken in amounts of 500 to 600 milligrams or less.
It’s a good idea to talk to your doctor to see how much calcium and vitamin D you need daily. Additionally, your physician can help you determine if supplementation is beneficial.
Effect of Calcium and Vitamin D Supplementation on Blood Pressure
Experimental and epidemiologic studies suggest that calcium and vitamin D supplements may lower blood pressure. We examined the effect of calcium plus vitamin D supplementation on blood pressure and the incidence of hypertension in post-menopausal women. The Women’s Health Initiative calcium/vitamin D trial randomly assigned 36,282 post-menopausal women to receive 1000 mg of elemental calcium plus 400 IU of vitamin D3 daily, or placebo, in a double-blind fashion. Change in blood pressure and the incidence of hypertension were ascertained. Over a median follow-up time of 7 years, there was no significant difference in the mean change over time in systolic blood pressure (0.22 mm Hg, 95% CI −0.05 – 0.49 mm Hg) and diastolic blood pressure (0.11 mm Hg, 95% CI −0.04 – 0.27 mm Hg) between the active and placebo treatment groups. This null result was robust in analyses accounting for non-adherence to study pills and in baseline subgroups of interest, including Blacks, women with hypertension or high levels of blood pressure, with low intakes of calcium and vitamin D, or low serum levels of vitamin D. In 17,122 non-hypertensive participants at baseline, the hazard ratio for incident hypertension associated with calcium/vitamin D treatment was 1.01 (95% CI 0.96 – 1.06.) In postmenopausal women, calcium plus vitamin D3 supplementation did not reduce either blood pressure or the risk of developing hypertension over seven years of follow-up.
The role of calcium in the prevention and treatment of hypertension is controversial, despite decades of study. An overall healthy dietary pattern that is rich in calcium from low-fat dairy products, fruits and vegetables has been shown to lower blood pressure substantially compared to a typical diet higher in fat and sodium and lower in calcium, magnesium, potassium and fiber.1–4 However, meta-analyses5–12 and systematic reviews13 of the epidemiologic and clinical trial evidence regarding dietary intake of calcium as a single nutrient have generally concluded that the effect on systolic blood pressure (BP) lowering is small, on the order of 2 mm Hg. The effect on diastolic BP, if any, may be even smaller. Nevertheless, at a population level, sustained BP lowering of this degree by calcium supplementation could have important benefits on cardiovascular disease.
Although the relation between vitamin D and BP has been less studied, two small, short-term intervention studies suggest that vitamin D, either as ultraviolet light exposure or as an oral supplement, may lower BP.14, 15 In addition, the risk of incident hypertension was lower in a 4-year prospective study among men and women with higher plasma levels of 25(OH) vitamin D.16 Animal studies have also shown that oral supplementation with vitamin D lowered blood pressure in hypertensive rats; in this model vitamin D inhibited renin expression in the juxtaglomerular apparatus and inhibited smooth muscle proliferation.17–20
Most individual trials of calcium supplementation (with or without vitamin D) have been relatively small, short in duration or both. Meta-analyses and reviews have called for high-quality, long-term studies including subgroups that might have greater BP lowering from calcium supplementation, such as individuals with elevated BP or hypertension (especially low renin or “salt-sensitive” hypertension), Blacks, or those with habitual low intake of calcium or vitamin D.21–24 The Women’s Health Initiative included a methodologically rigorous randomized, double-blind, placebo-controlled trial of dietary supplementation with calcium plus vitamin D supplementation and long-term follow-up. We examined the effect on BP and the incidence of hypertension in this study of 36,282 post-menopausal women. Because of the large size of the trial we were able to examine subgroups that might have differing degrees of benefit.