Vitamin A For Pigmentation


Pigmentation is a big problem for some people, but it doesn’t have to be.

Pigmentation is the darkening of skin, and it can occur due to sun exposure, hormonal changes, trauma, or even acne. While there are some treatments available for pigmentation (like chemical peels and laser therapy), they can be expensive and painful—and in some cases, the effects are short-lived.

Fortunately, there are natural remedies that can help reduce your skin’s pigmentation over time. One of the most effective natural remedies is vitamin A. Vitamin A is found in foods like carrots, sweet potatoes and leafy greens; it’s also available in supplement form at any grocery store or health food store.

Vitamin A For Pigmentation


April 4, 2020

If you have used a skincare product for hyperpigmentation before, you may have noticed it contains some vitamins. It may seem odd for a topical medication to have vitamins, especially because vitamins are traditionally taken orally. The reason most skincare products have them is that vitamins have been shown to improve the skin when applied topically. The problem is that most products promote vitamins like some magical snake oil with equally magical results.

Let’s take a step back and ask some real questions. Do vitamins work for the skin? What other things should you know about vitamins for hyperpigmentation? Here at ClearifiRx, we use science to back all our skincare products. That’s why we have prepared this objective science-focused guide to answer all your vitamins for hyperpigmentation questions.

How Do Vitamins For Skin Work?

Vitamins are essential nutrients used in the body for various functions. One of the functions is to ensure cellular health. When your body has the right vitamins in the right quantities, this can promote cell health, especially skin cells. Studies have also shown that applying vitamins directly to the skin can have positive effects on the skin. That is because the skin absorbs the vitamins, making the nutrients immediately bioavailable for your skin cells to use. Such a targeted application helps improve the health of your skin cells rapidly, resulting in healthier, brighter, and more glowing skin.

Which Vitamins Are Best For Skin Pigmentation?

A variety of factors can cause skin hyperpigmentation. As such, different types of hyperpigmentation conditions respond to different vitamin treatments.

For example, Vitamin A, belonging to the family of retinoids, is excellent for exfoliating dead skin. (Skin exfoliation improves cell turnover, hastening how fast hyperpigmentation fades.) If you have dark spots from acne, this vitamin is an excellent treatment option.

Another example is vitamin C, which promotes collagen production. This is a great post-inflammatory hyperpigmentation vitamin for sun-damaged skin with sunspots. For the best results, we recommend a carefully formulated blend of vitamins, such as the ones ClearifiRx doctors prescribe.

Which Vitamins Are Good For Lightening Dark Spots?

Skin whitening or lightening is the most effective way to lighten dark spots. Vitamins can be used to lighten your skin and lighten dark spots. Three of the best vitamins for lightening dark spots are vitamin C, vitamin B12, and vitamin E.

Vitamin C helps your skin produce more collagen while inhibiting the formation of melanin. Vitamin B12 also promotes collagen formation while supporting the growth of new skin cells. Vitamin E is widely used to treat scarring, which can help lighten dark spots.

How Long Do Vitamins For Hyperpigmentation Take To Work?

The formulation you are using will determine how fast you get results. Here at ClearifiRx, we formulate all our medications specifically for each patient. We evaluate your case, and depending on the formulation we recommend, estimate the time required to see visible results. However, our general estimate is that vitamin skin treatment starts showing results after two weeks of application. Applying only one vitamin may also slow down the onset of visible results.

Which Vitamins Should I Take For Overall Skin Health?

Each vitamin you use has a positive impact on your skin. That is why it is best to use a formulation with at least four vitamins. The best vitamins to use for overall skin health are vitamins C, E, B12, and A.

Although vitamin D is essential for skin health, its primary role is the promotion of melanin formation, which may cause more skin darkening. Keep in mind the best results will come from a tailor-made formulation, which one of the ClearifiRx doctors can recommend and formulate for you.

Can Vitamins Cause Skin Problems?

Vitamins can sometimes cause skin problems, but only in rare situations. In most cases, the skin problem is caused by either an allergic reaction to the vitamin, a vitamin deficiency, or excessive quantities in the body (toxicity). Allergic reactions can happen with any vitamin, as it depends on an individual’s immune response to the vitamin. Vitamin deficiency such as a hyperpigmentation vitamin b12 deficiency is linked to genetic disorders and severe malnutrition, both of which are extremely rare. Vitamin toxicity, especially vitamin A, can lead to skin problems, as well as other health complications.

Can I Take Vitamins For Skin And Hormones?

Hormonal factors can cause some skin hyperpigmentation conditions. One such condition is hormonal acne. Like any other acne, this type of acne can result in dark spots. Some vitamins can help reduce this type of hyperpigmentation. For example, B and C vitamins can be taken both orally and applied to the skin to help manage hormonal acne. Vitamin C also helps collagen growth which helps skin healing from hormonal acne. Vitamin C is also especially useful as it also acts as a mild antibacterial agent. When applied regularly to the skin, Vitamin C helps fight bacteria that make hormonal acne worse.

Can I Find Enough Vitamins For Skin In Food?

Vitamin intake is vital to a healthy body. However, most dietary vitamin intake only covers general bodily use of the nutrients. If you want to have targeted results for skin conditions such as melasma, skin spots, and other hyperpigmentation conditions, topical vitamin application is necessary. Orally taking vitamins for the skin can also expose you to vitamin toxicity if you take too much. A professionally formulated vitamin skin treatment is the best option for optimal results.

Do I Need To See A Doctor Before Using Vitamins For My Skin?

While it is not necessary to see a doctor before using vitamins for your skin, seeing a doctor will give you the best results. Most vitamin preparations on the market are generally safe to use. However, they are generically formulated, meaning you may not get the results you want.

ClearifiRx vitamin skin treatments are formulated for your specific skin type and condition. We also follow up with you and, if necessary, adjust the treatment to ensure you get the best results.

What Are Some Side Effects Of Taking Vitamins For Hyperpigmentation?

The most common side effect of using vitamins for your skin is mild, temporary irritation. When you apply vitamins for the first time, you may feel a slight warm sensation or some mild irritation that goes away after a few minutes. In rare cases, some people may experience an allergic reaction characterized by redness, soreness, and mild pain. In such cases, washing the affected area with water often resolves the issue. ClearifiRx works with each client to minimize any side effects and effectively manage any that occur.

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Last Words

Vitamins are generally helpful in treating skin hyperpigmentation. However, the results depend on the type of vitamin and formulation. For best results, we recommend working with a dermatologists who will evaluate your skin type and condition and formulate a customized serum for you. We’ve repeatedly seen clients benefit from this approach compared to using over-the-counter skin vitamin formulations.

oral vitamin a for skin

Purpose: Previously, we reported the results of a Phase III, placebo-controlled trial in 2297 randomized participants with moderately severe actinic keratoses wherein 25000 IU/day vitamin A caused a 32% risk reduction in squamous cell skin cancers. We hypothesized that dose escalation of vitamin A to 50000 or 75000 IU/day would be both safe and more efficacious in skin cancer chemoprevention.

Experimental design: One hundred and twenty-nine participants with severely sun-damaged skin on their lateral forearms were randomized to receive placebo or 25000, 50000, or 75000 IU/day vitamin A for 12 months. The primary study end points were the clinical and laboratory safety of vitamin A, and the secondary end points included quantitative, karyometric image analysis and assessment of retinoid and rexinoid receptors in sun-damaged skin.

Results: There were no significant differences in expected clinical and laboratory toxicities between the groups of participants randomized to placebo, 25000 IU/day, 50000 IU/day, and 75000 IU/day. Karyometric features were computed from the basal cell layer of skin biopsies, and a total of 22600 nuclei from 113 participants were examined, showing statistically significant, dose-response effects for vitamin A at the 25000 and 50000 IU/day doses. These karyometric changes correlated with increases in retinoic acid receptor alpha, retinoic acid receptor beta, and retinoid X receptor alpha at the 50000 IU/day vitamin A dose.

Conclusions: The vitamin A doses of 50000 and 75000 IU/day for 1 year proved safe and equally more efficacious than the 25000 IU/day dose and can be recommended for future skin cancer chemoprevention studies.

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